CBD stands for Cannabidiol and is the second most actively used cannabis or marijuana. It is derived from the hemp plant, which serves as a substitute for marijuana. The concept of bioavailability is touched upon through the topic of the “best” way to intake CBD. So, to know bioavailability and its effects on individuals’ experience with CBD oil learn this here now by reading on.
Bioavailability refers to how much and at what rate does something, a liquid/solid gets absorbed in your bloodstream. It is highly significant to understand the bioavailability of a substance, to determine how much an individual needs to ingest and in what form, to achieve the expected benefits. The bioavailability of CBD largely depends upon how one ingests it in their system.
CBD through intranasal bioavailability
Studies have proven that CBD intake through vapes and e-cigarettes has the highest bioavailability, ranging from 34-46 percent, and going up to 56 percent. When CBD is consumed through the nasal passage, it gets a direct entry into the lungs, which further gets easier access to the bloodstream, allowing CBD to attach to appropriate endocannabinoid receptors. With each repeating breath, you draw in more CBD that is efficiently absorbed, thereby proving to acquire higher levels of bioavailability and rendering quick effects.
CBD sublingual and oral bioavailability
CBD oil consumption through the sublingual method, which means dropping the oil under the tongue, for about 60-120 seconds, has been gaining popularity. Studies have proven sublingual’s bioavailability to be ranging from 13-19 percent, going up to 35 percent. The trick to get the desired effects in about 20 minutes is by dropping the oil in the correct area so that it can enter the bloodstream through the sublingual gland. If swallowed too soon or dropped improperly, it will be like oral ingestion which offers relatively lesser bioavailability.
Oral ingestion of CBD oil is achieved in the forms of eating, drinking, or daily vitamins, therefore it is quite popular and determined to be the easiest way. However, as per studies, oral ingestion provides bioavailability ranging from 10-16 percent, going as low as 6 percent. It renders the least amount of CBD bioavailability because, during oral ingestion, the substance passes through the digestive system first and is then released into the bloodstream, to reach the appropriate receptors. This entire process takes up to 2 hours and during it, most of CBD properties are lost to the liver and the digestive tract, giving the least amount of desired effects.
CBD topical bioavailability
The topical method to intake CBD requires no digestive system, as it directly contacts with the endocannabinoid receptors under the skin. As the skin is designed to protect the insides from the externalities, it is mostly non-porous; therefore the lotion might need to be applied rigorously and liberally in an accurate location, to get the maximum benefits. The exact bioavailability of topicals is not quantified but is expected to below. The topical method does not surpass all the dermal layers of the skin, therefore is unable to enter the bloodstream and unable to connect with the brain, hence this method cannot resolve diseases like epilepsy and PTSD. It is effective to get immediate relief from chronic pains and muscle-related pains.